KMID : 0363220190570060332
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Korean Journal of Dermatology 2019 Volume.57 No. 6 p.332 ~ p.334
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Acquired Reactive Perforating Collagenosis as a Preceding Manifestation of Hodgkin¡¯s Lymphoma
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Lee Soo-Young
Bang Chul-Hwan Park Young-Min Lee Jun-Young Lee Ji-Hyun
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Abstract
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A 40-year-old man presented with pruritic, multiple, variable-sized, erythematous umbilicated papules on the trunk and both extremities for 4 months. He was diagnosed with Hodgkin¡¯s lymphoma (stage IIA) after histopathologic examination of a neck mass that developed a month ago. A punch biopsy was performed on his right lower leg.
Histological examination showed transepidermal elimination of the degenerated collagen. Masson¡¯s trichrome staining was performed to distinguish collagen fibers from the muscular tissue; using Masson¡¯s stain, the collagen appeared as a bluish color crossing from the dermis to the epidermis. The diagnosis of acquired reactive perforating collagenosis was made. The skin lesions showed much improvement after 6 cycles of doxorubicin, bleomycin, vinblastine, and dacarbazine chemotherapy. Acquired perforating disorders are a group of cutaneous disorders that occur in adults with chronic kidney disease or diabetes mellitus. Cases of acquired perforating disorders associated with Hodgkin¡¯s lymphoma have been rarely reported in the English literature. To our knowledge, this is the first case of acquired reactive perforating collagenosis in a Korean patient with Hodgkin¡¯s lymphoma.
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KEYWORD
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Acquired perforating disorder, Acquired reactive perforating collagenosis, Hodgkin¡¯s lymphoma
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